YMC's preparative stationary phases are available in ton scale in a variety of product variants:
Particle Sizes
7 - 10 - 15 - 20 - 50 - 75 - 150 μm
Pore Sizes
8 - 12 - 20 - 30 nm
C1 to C18 and customised modifications
(available in up to 200 kg lots)
Advantages
- Extended pH range 2-10
- Alkaline CIP procedures
- Flexibility in method
development - Longer lifetimes
- Improved loadability
- Compatible with 100% aqueous conditions
Available Stationary Phases:
Hybrid Silica-based
- YMC-Triart Prep C18-S
- YMC-Triart Prep C8-S
- YMC-Triart Prep Bio200 C8
- YMC-Triart Prep Phenyl-S
- YMC-Triart Prep C4-S
Silica-based
"Almac has been working with YMC and APEX Scientific on various projects for over 5 years – from mg impurity isolation to multi-kg purification and have found the level of technical support and guidance exemplary when using their products. This has ranged from advice on packing large DAC columns to the best media for a particular separation. Furthermore, YMC has presented on a number of different topics at Almac, which has increased our toolbox of purification technologies now regularly utilised in-house."
Steve McIntyre, Almac Group Ltd. (UK)
YMC-Triart Prep C18-S | YMC-Triart Prep C8-S | YMC-Triart Prep Bio200 C8 | YMC-Triart Prep Phenyl-S | YMC-Triart Prep C4-S | |
Base Material | organic / inorganic hybrid silica | ||||
Modification | C18 | C8 | C8 | phenyl | C4 |
Particle Size [µm] | 7, 10, 15, 20 | 10, 15, 20 | 10 | 10 | 10 |
Pore Size [nm] | 12 | 12 | 20 | 12 | 12 |
Surface Area [m²/g] | 360 | 360 | proprietary | 360 | 360 |
Bonding Type | trifunctional | ||||
Endcapping | yes | ||||
pH Range | 2.0 - 10.0 | ||||
100% Aqeuous Eluents | yes | - | - | yes |
YMC*Gel ODS-A-HG | YMC*Gel ODS-AQ-HG | YMC*Gel C8-HG (Octyl) | YMC*Gel C4-HG (Butyl) | YMC*Gel TMS-HS | YMC*Gel Ph-HG (Phenyl) | YMCbasic | |
Base Material | high grade silica | ||||||
Modification | C18 | C18 | C8 | C4 | C1 | Phenyl | C8 |
Particle Size [µm] | 10, 15, 20, 50 | 10, 15, 20, 50 | 10, 15, 20, 50 | 10, 15, 20, 50 | 10, 15, 20, 50 | 10, 15, 20, 50 | 10 |
Pore Size [nm] | (8), 12, 20, 30 | 8, 12, 20 | 12, 20, 30 | 12, 20, 30 | 12, (20, 30) | 12, (20, 30) | 20 |
Surface Area [m²/g] | (510), 330, 175, 100 | 510, 330, 175 | 330, 175, 100 | 330, 175, 100 | 330, (175, 100) | 330, (175, 100) | proprietary |
Carbon Load [%] | 17, 12, 7 | 15, 14, 10 | 10, 7, 4 | 7, 5, 3 | 4 | 9 | 7 |
pH Range | 2.0 - 7.5 | ||||||
100% Aqueous Eluents | - | yes | - | - | - | - | - |
The basis for every successful separation is the selection of the appropriate stationary phase. YMC offers one of the world‘s largest portfolios of selectivities, designed to handle even the most demanding separations.




Problem
Silica materials are unsuitable for alkaline wash conditions, because of their poor stability at high pH.

Pore Size (nm) | Surface Area (m²/g) | Recommendation |
12 | 330 | Suitable for the majority of separations For most organic compounds For peptides less than 20 kDa Higher surface area and sample loading than 20 nm and 30 nm |
20 | 175 | For peptides and smaller proteins from 10 kDa to 50 kDa For bulky organic compounds Higher surface area and higher sample loading than 30 nm |
30 | 100 | For large proteins and biomolecules larger than 40 kDa For organic compounds with excessive retention on smaller pore size |

Title | Document Type | Language | Download |
Application Note | EN | ||
Application Note | EN | ||
Application Note | EN | ||
Application Note | EN | ||
Application Note | EN | ||
Application Note | EN | ||
Brochure | EN | ||
Brochure | EN | ||
Care and Use Instructions | EN | ||
Care and Use Instructions | EN | ||
Care and Use Instructions | EN | ||
Care and Use Instructions | EN | ||
Expert Tip | EN | ||
Flyer | EN | ||
Flyer | EN | ||
Flyer | EN | ||
Overview | DE | ||
Overview | DE | ||
Overview | EN | ||
Overview | EN | ||
Overview | EN | ||
Overview | EN | ||
Poster | EN | ||
Poster | EN | ||
Poster | EN | ||
Poster | EN | ||
Product Information | EN | ||
Technical Note | EN | ||
Technical Note | EN | ||
Technical Note | EN | ||
Technical Note | EN | ||
Technical Note | EN | ||
Technical Note | EN |

Please contact YMC for pricing or specific solutions for your purification process.
Julia Bartmann
Product Manager Bulk Media
ph. +49 2064 427-260
Particle Size | YMC-Triart Prep C18-S | YMC-Triart Prep C8-S | YMC-Triart Prep Bio200 C8 | YMC-Triart Prep Phenyl-S | YMC-Triart Prep C4-S |
7 µm | TAS12S07 | ||||
10 µm | TAS12S11 | TOS12S11 | TOB20S11 | TPS12S11 | TBS12S11 |
15 µm | TAS12S16 | TOS12S16 | |||
20 µm | TAS12S21 | TOS12S21 |
Other particle and pore size combinations are available on request.
Example of existing customised materials:
TOS20S11, YMC-Triart Prep C8-S, 20 nm / 200 Å, 10 µm
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | AAG12S11 | AAG20S11 | AAG30S11 |
15 µm | AAG12S16 | AAG20S16 | AAG30S16 |
20 µm | AAG12S21 | AAG20S21 | AAG30S21 |
50 µm | AAG12S50 | ||
75 µm | AA12S75 | ||
150 µm | AA12SA5 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | AQG12S11 | AQG20S11 | AQG30S11 |
15 µm | AQG12S16 | AQG20S16 | AQG30S16 |
20 µm | AQG12S21 | AQG20S21 | AQG30S21 |
50 µm | AQG12S50 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | OCG12S11 | OCG20S11 | OCG30S11 |
15 µm | OCG12S16 | OCG20S16 | OCG30S16 |
20 µm | OCG12S21 | OCG20S21 | OCG30S21 |
50 µm | OCG12S50 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | BUG12S11 | BUG20S11 | BUG30S11 |
15 µm | BUG12S16 | BUG20S16 | BUG30S16 |
20 µm | BUG12S21 | BUG20S21 | BUG30S21 |
50 µm | BUG12S50 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | TMG12S11 | TMG20S11 | TMG30S11 |
15 µm | TMG12S16 | TMG20S16 | TMG30S16 |
20 µm | TMG12S21 | TMG20S21 | TMG30S21 |
50 µm | TMG12S50 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size/Pore Size | 12 nm | 20 nm | 30 nm |
10 µm | PHG12S11 | PHG20S11 | PHG30S11 |
15 µm | PHG12S16 | PHG20S16 | PHG30S16 |
20 µm | PHG12S21 | PHG20S21 | PHG30S21 |
50 µm | PHG12S50 |
Other particle and pore size combinations are available on request.
Stationary phases based on classical silica material available on request.
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)
Particle Size | YMCbasic |
10 µm | BA99S11 |
Typical pack sizes:
Laboratory scale: smallest amount is 100 grams up to 4 kg PE bottle
Industrial scale: more than 4 kg in double lined PE bags inside metal drums (10 or 25 kg drums)