Metal-coordinating compounds such as chelating agents can interact with the metallic surface of the column body, frits, etc. This can lead to decreased recovery, deteriorating peaks and sample carry-over.To overcome these challenges truly inert column hardware such as YMC-Accura columns can be used.
In this applications note the chelating agents 8-hydroxyquinoline and hinokitiol were analysed using a bioinert coated YMC-Accura Triart C18 column and compared to the corresponding stainless-steel column.
Bioinert coated YMC-Accura Triart columns provide:
- Higher recovery
- Improved peak shapes
- Greater reproducibility
Download the Application Note for full method details.
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