(Semi)preparative IEX columns – porous or non-porous BioPro IEX

If you are looking for ion exchange columns (IEX) that have convincing properties, then YMC’s BioPro IEX columns are the first choice. BioPro IEX columns provide high column stabilities in analytical and (semi)preparative scale.

The non-porous exchanger columns BioPro IEX QF and BioPro IEX SF offer outstanding efficiencies, so that even small sample variations can readily be detected and purified. The porous BioPro IEX QA and BioPro IEX SP columns provide high capacities for high-load separations.

The following (semi)preparative options are available:




Particle size



Non-porous AEX

6 µm

100 x 10 mm ID

100 x 20 mm ID

100 x 30 mm ID


Non-porous CEX


Porous AEX

6 µm

100 x 10 mm ID

100 x 20 mm ID


Porous CEX


*stainless steel hardware

BioPro IEX columns are designed for analysing monoclonal antibodies, proteins and peptides as well as oligonucleotides with high resolutions.

For further information about BioPro IEX columns, check out the YMC BioLC catalogue or visit our homepage IEX columns.


Very helpful in everyday laboratory work: (U)HPLC method development, oligonucleotides in poster format for the laboratory

You will receive practical step-by-step instructions for (U)HPLC method development of oligonucleotides in a clear poster format. From basics such as selecting a suitable stationary phase to buffer concentrations worth knowing, you have everything in view for a robust method. Of course, all development steps are illustrated with chromatographic data. Therefore it is also a very successful tool for internal training purposes!

Analytical Study of the Separation Behaviour of Oligonucleotides on IP-RPLC
Behaviour of Phosphodiester and Phosphorothioate Oligo-RNAs

➡️ Get your Poster here!

For further information about the applied YMC-Triart and bioinert YMC-Accura Triart columns, check out the corresponding brochures.


Informative white paper: Reproducible LC results on PEGylated proteins

Polyethylene glycol (PEG) is a widely used substance to modify peptides, proteins or other biologics for therapeutic applications. However, the analytical characterization of PEGylated proteins can be very challenging. You can find out how to successfully master these tasks in this new white paper from YMC in cooperation with Ligand Pharmaceuticals Inc. (US)!
Particular highlights are:

Analytical characterization of PEGylated proteins
State-of-the-art methods for charge variant analysis
Proven methods for the analysis of charge variants with the BioPro IEX SF column

For further information about YMC’s BioPro CEX columns, check out the IEX section of the YMC BioLC catalogue or visit our homepage.

Fig.: IEX of full-sized and expanded trace PEGylated protein using YMC’s BioPro IEX SF column.