Increased yield in oligonucleotide purification by continuous chromatography!
MCSGP is an interesting alternative for purifying mixtures of substances where cost-effectiveness is important. In classic batch chromatography, purity and yield often compete with each other. In MCSGP applications, both are achieved simultaneously. Therefore, highly efficient stationary phases like YMC-Triart Prep C8-S are the perfect choice.
This paper shows convincing performance data for demanding oligonucleotide purifications: The yield can be increased up to 91.6 % at 94.2% purity! This eliminates the need for renewed chromatography and the QA effort is significantly reduced.
Find more information about YMC-Triart Prep on the YMC homepage.
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