Bioinert (U)HPLC columns for bio-separations and coordinating compounds

Are you dealing with demanding substances that tend to coordinate with metals?
Are you looking for an inert solution for your peptide/protein, (oligo)nucleotide or sensitive small molecules?

This is the solution for your problems! The bioinert YMC-Triart columns are fully biocompatible due to their PEEK lined stainless steel column bodies and the use of PEEK frits. You can achieve excellent peak shapes for sensitive compounds. The prevention of carry over makes them an ideal choice for highly sensitive LC/MS analyses.


  • Excellent peak shapes and high sensitivity
  • Reproducible results day-after-day
  • No carry-over effects
  • Ideal for highly sensitive LC/MS analyses
  • High pressure limits

Ideal choice for

  • Sensitive proteins or peptides
  • Nucleotides, oligonucleotides
  • Metal coordinating compounds

Check out our new flyer to discover more about biocompatible YMC-Triart metal-free columns.

LC-HRMS analysis of the antisense oligonucleotide Mipomersen (Kynamro®)

Are you looking for a method to analyse antisense oligonucleotides using LC-MS?

This new application note shows the LC-HRMS analysis of antisense oligonucleotides (ASOs) using the separation of Mipomersen (commercially available as Kynamro®) according to Sun et al. as the example. A YMC-Triart C8 metal-free column was used which is an excellent choice for oligonucleotide analyses because of its full biocompatibility providing sharp peaks, high sensitivities and no carry-over.

Download this application note to discover more about the analysis of antisense oligonucleotides.

If you are interested in more information about YMC-Triart metal-free columns, check out our new flyer.

Join interesting BioLC talks at Wiley Analytical Science Conference 2021!

In cooperation with Wiley Analytical Science, YMC invites you to participate at an interesting BioLC webinar which will consist of two parts:

Part I, April 22, 2021
Characterisation and Quantification of Biomolecules
Presented by the Institute for Energy- and Environmental Technology e. V. (IUTA)

Part II, April 22, 2021
Analysing Antibodies by Different LC Separation Modes
UHPLC/HPLC Solutions in RP, SEC, IEX and HIC
Presented by YMC Europe

The talks are especially of interests for bioanalysts, pharmacists, instrumental analysts, quality inspectors and users of 2D-HPLC.

Please find further details about the conference and register here. We look forward to see you there!