The greatest challenge in monitoring highly toxic chlorophenols in the environment, is their structural similarity. Compounds of this group often differ only in the amount and/or position of the chlorine substituents. Separation by HPLC requires high steric selectivity of the stationary phase.
This required selectivity is provided by YMC-Triart C18 ExRS columns due to their high carbon content and the small pore size of the stationary phase, which enables steric recognition.
In this Application Note baseline separation of seven chlorophenols is achieved using a YMC-Triart C18 ExRS column.