YMC Accura columns are the solution for researchers working with challenging phosphate-rich molecules or metal-coordinating compounds. These bioinert columns feature an advanced inert coating, designed to prevent peak tailing and carry-over, while delivering optimal recovery rates.

Their seamless compatibility with MS detectors, as demonstrated in this technical note, ensures enhanced workflow accuracy, making them an indispensable tool for high-sensitivity applications.

Optimise your LC-MS results with YMC Accura columns today!

Discover their performance — read the technical note for details.

Achieve unparalleled separation efficiency of a site-specific antibody-drug-conjugate (ADC) with the YMC-Triart Bio C4 column. This advanced reversed-phase (RP) column features robust organic/inorganic hybrid silica particles with a 300 Å pore size, optimised for biopharmaceutical separations.

Key Features:

• Balanced hydrophobicity: The butyl (C4) functionalisation provides optimal hydrophobic interactions, essential for precise drug-to-antibody ratio (DAR) determinations.
• High temperature stability​: Engineered to withstand temperatures up to 90°C, facilitating the separation of large biomolecules, including intact antibodies and ADCs.
• LC-MS compatibility: Delivers excellent peak shapes with mobile phases containing formic acid, enhancing sensitivity in mass spectrometry workflows.