YMC i-Mail January 2023

Case Study:

How to reduce the costs for preparative LC processes

Improve the cost efficiency of your process by selecting the appropriate stationary phase! Even though the preparative stationary phase itself represents only a small proportion of the overall costs of preparative processes, its choice is the most important step during the process development. It dictates important parameters such as the required amounts of solvents and the lifetime of the stationary phase. These and further aspects have a significant influence on the operational costs which determine the cost efficiency of the overall process.

In cooperation with an insulin manufacturer, several stationary phases were screened with real insulin samples in order to perform a detailed cost calculation. Download the Case Study and learn how to save costs up to 40% by using YMC-Triart Prep Bio200 C8 for your purification.


Online Seminar:

Are you new to the field of preparative HPLC?

Do you want to learn how to develop a purification process?

Then, this training will be a very good introduction! You will learn all the important basics of preparative liquid chromatography:

  1. Method selection and optimisation on an analytical scale
  2. Determination of optimal loading
  3. Final scale-up

Your own process development work will be further supported by expert tips and examples of process optimisations.



Contents and Learning Objectives

  • Differences between analytical and preparative chromatography
  • Important preparative process parameters: purity, yield and productivity – the “triangle” of preparative chromatography
  • Outline of preparative method development: three steps to your preparative method

16.03.2023, 10 am (CET), duration 2 hours
18.10.2023, 10 am (CET), duration 2 hours

You can find more information here.


Seminar registration