YMC i-Mail December 2024

Streamline your mAb and ADC analysis with YMC's comprehensive Application Collection

Maximise efficiency and precision in the analysis of monoclonal antibodies (mAbs) and
antibody-drug-conjugates (ADCs) with YMC's tailored solutions. This collection of applications combines proven reliability with cutting-edge technologies to optimise your workflows and save valuable lab time.

From intact to fragmented mAbs, DAR determination, or native LC-MS techniques, YMC columns provide highly sensitive and reliable methods using ion exchange (IEX), size exclusion (SEC), hydrophobic interaction (HIC), and reversed-phase liquid chromatography (RP).

Equip your lab with faster, more precise (U)HPLC analyses that directly support your success.

Download the Application Collection today and ensure you always have the best solutions at hand!

 

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No ion pair reagents required

High-performance oligonucleotide analysis with RP-MS

Discover an innovative RP-MS approach for oligonucleotide analysis, that replaces ion-pair reagents with ammonium bicarbonate. This advanced RP-MS method delivers unmatched performance.

Even in challenging reconstituted plasma samples, this technique excels – achieving exceptional sensitivity, precise separation, and no carry-over. The result? Reliable, reproducible data you can trust!

Ready to optimise your workflow? Download the Application Note and take your oligonucleotide analysis to the next level!

For detailed insights, download the Application Note.
 

Fig. 1: Extracted ion chromatograms of the antisense (left) and sense strands (right) of lumasiran in reconstituted plasma at the LLOQ [1].

Discover further innovative applications in the YMC Oligonucleotide Column brochure or in the application database.

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Download Application Note

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