Martin Klaßen from the Institute for Energy and Environmental Technology e.V. (IUTA) presents alternative methods for the characterisation of native and associated proteins in this online presentation. He focuses on the analysis of monoclonal antibodies and their aggregates. For this purpose, Raman spectroscopy is first discussed in detail, as well as an amplification technique for the surfaces. In the second part of the presentation, Klaßen goes into the analysis of virus-like particles. This is about the characterisation of virus-like particles and a possible method.