YMC-Actus

Innovative (Semi)preparative HPLC Columns

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Guide to Semi-Preparative Columns for HPLC Applications

What Are Semi-Preparative HPLC Columns?

Semi-preparative HPLC columns are designed for purifying larger sample amounts compared to standard analytical columns. They bridge the gap between analytical and preparative chromatography by offering high resolution with increased loading capacity. These columns are ideal for method scaling, fractionation, and compound isolation in pharmaceutical development, biotechnology, and chemical research. YMC’s Actus semi-preparative columns combine robust DAC (Dynamic Axial Compression) packing knowledge with innovative hardware design to ensure excellent stability and efficiency, even under demanding flow or gradient conditions.

Applications of Semi-Preparative HPLC Columns

Semi-preparative columns are widely used in:

  • Compound purification for drug discovery and development

  • Isolation of impurities and degradation products

  • Method transfer from analytical to preparative scale

  • Preparative separations in life science and chemical analysis

Their compatibility with a broad range of stationary phases and mobile phases ensures flexibility for a wide range of compound classes and chromatographic conditions.

Benefits of YMC Actus Semi-Preparative Columns

YMC Actus columns are engineered for long-lasting performance under high stress. The precision-packed hardware minimizes band broadening and ensures outstanding reproducibility. Their high flow tolerance and rugged construction make them the ideal choice for high-throughput purification and semi-preparative HPLC workflows.

Find the Right Semi-Preparative Column for Your Needs

Whether you’re scaling up your method or purifying critical samples, YMC Actus semi-preparative HPLC columns provide reliable performance and high throughput. Their robust design and flexibility support demanding separation goals across industries.

 

Need support selecting the right semi-prep column for your method? Contact YMC Europe for expert consultation.

Contact us for consultation
  • YMC Europe GmbH
  • Phone +49 2064 427-0
  • Schöttmannshof 19
  • Fax +49 2064 427-222
  • D-46539 Dinslaken