YMC i-Mail November 2025

MacroSep IEX Q

Large Biomolecules? Large Pore!

Whether plasmid DNA, VLPs, or AAVs – large biomolecules quickly push conventional process resins to their limits. Standard pore? Too small. Loadability? Too low. Productivity? Restricted.

This is where MacroSep IEX Q comes in: With its unique macro-porous structure (900 nm), even large molecules can fully access the binding sites. The result: significantly higher dynamic binding capacity – and greater productivity in your purification process.

Our new Technical Note shows in a direct comparison why MacroSep IEX Q outperforms other materials – and how you can benefit from it in practice.

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Sustainability in Focus

Sustainability is gaining increasing importance in biopharmaceutical production. The right process resin makes a decisive contribution: high binding capacity, excellent separation efficiency, and long lifetime significantly reduce resource consumption. The perfect complement to this are the robust YMC glass columns, which stand out not only for their durability but also for their easy handling.

The combination of innovative resins and reusable glass columns creates a sustainable solution that unites ecological responsibility with efficient processes.