YMC i-Mail August 2026

Efficient pDNA Purification

A study conducted by Richter Biologics using YMC’s MacroSep IEX Q explores how resin loading affects yield and RNA removal in AEX-based pDNA purification. The results: MacroSep IEX Q achieved high step yields while reducing residual RNA to approximately 0.5% under high-loading conditions.

Discover the full results in our new Application Note!
 

MacroSep IEX Q

MacroSep IEX Q The Right IEX Resin for Your Plasmid Purification

 

 

The purification of large biomolecules like plasmid DNA often pushes conventional ion exchange resins to their limits – especially when high loading and efficient separation are required. YMC addresses this challenge with MacroSep IEX Q, a macro-porous anion exchange resin specifically developed for the purification of large biomolecules. Unlike traditional IEX materials, MacroSep IEX Q features a macro-porous structure that enables reliable separation of large particles such as viral vectors.

See for yourself.